产品货号:
Z39493
中文名称:
PTEN抗体
英文名称:
Anti-PTEN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PTEN Antibody |
指标别名 | 10q23del;Bannayan Zonana syndrome;BC005821;BZS;ITGA 2;MGC11227;MHAM;MMAC1;Multiple hamartoma (Cowden syndrome);phosphatase and tensin homolog;PTEN;PTEN1;TEP1 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ICC/IF,FCM |
基因名称 | PTEN |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human PTEN |
实际分子量 | 47~55KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | PTEN is also known as BZS,DEC,CWS1,GLM2,MHAM,TEP1,PTEN1.It is mapped to 10q23.3.This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency.The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase.It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases.Unlike most of the protein tyrosine phosphatases,this protein preferentially dephosphorylates phosphoinositide substrates.The PTEN structure reveals a phosphatase domain that is similar to protein phosphatases but also has an enlarged active site important for the accommodation of the phosphoinositide substrate. |
Uniprot ID | P60484 |
基因名全称 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 Flow cytometry (FCM) 1:20 |
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